Determination of oxytetracycline in milk samples by polymer inclusion membraneseparation coupled to high performance liquid chromatography
Pérez Silva, Irma
2012
Determination of oxytetracycline in milk samples by polymer inclusion membraneseparation coupled to high performance liquid chromatography.Irma Pérez-Silva, José A. Rodríguez, Ma. Teresa Ramírez-Silva, Ma. Elena Páez-Hernández.Analytica Chimica Acta, 718, 2012, 42?46.DOI:10.1016/j.aca.2011.12.057
Abstract
The determination of oxytetracycline in milk samples using a polymer inclusion membrane concept with high performance liquid chromatography (HPLC) was studied. The membranes developed are composed by cellulose acetate as polymer base, Cyanex 923 as carrier and o-nitrophenyl octyl ether as plasticizer. In the optimal conditions, the method exhibits good linearity in the range 0.03?0.20 mg L?1 with a limit of detection and quantification of 8.2 and 27.3 ?g L?1 respectively. The method was successfully applied to the analysis of milk samples with high selectivity.
