2017
Daniel Mendoza-Espinosa, Alejandro Alvarez-Hernández, Deyanira Angeles-Beltrán, Guillermo E. Negrón-Silva, Oscar R. Suárez-Castillo, and José M. Vásquez-Pérez,Inorg. Chem., 2017, 56(4), 2092-2099DOI: 10.1021/acs.inorgchem.6b02778
Abstract
Following a copper catalyzed alkyne azide cycloaddition (CuAAC)and N-alkylation protocols, we report the preparation of a hybrid N-heterocyclic/mesoionic [NHC(H+)-MIC(H+)][2I]2? salt (1) in high yields. The treatment ofsalt 1 with Cu2O and KI yields a second hybrid NHC/MIC proligand featuring atetraiodocuprate anion [NHC(H+)-MIC(H+)][Cu2I4]2? (2). Through selectivedeprotonation and metalation, both salts 1 and 2 can generate either the chelateheterodicarbene complexes (3) with the rare [NHC(M)MIC]+[MX2]? generalformula (M = PdII, RhI) or NHC-anchored/pendent triazolium species (4)[NHC(M)-MIC(H+)]. If the triazolium moiety of type 4 complexes isdeprotonated with KHMDS in the presence of a second metal center, a seriesof heterobimetallic complexes of the type [NHC(M)-MIC(M?)] (5) areachieved. Interestingly, the reaction of salt 2 with KHMDS yields the bimetalliccopper heterodicarbene (6) which can be a useful transfer reagent for the preparation of type 3 complexes. A variety of syntheticroutes for the preparation of complexes 3?5 and their full characterization in solution and in the solid state will be discussed.
Role of lipid peroxidation in biliary obstruction in the rat
Absolute configuration determination of 2-(2-oxo-3-indolyl)acetamide derivatives
Unimolecular rearrangements of ketene-O,O-acetals and fragmentations occurring in the gas phase
The absoluteconfiguration of cuauhtemone and related compounds
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea
13C NMR and crystallographic evidence of push-pull effects in furoindolic ?-enamino esters
Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor