2012
Vázquez-Arredondo, R. M., Suárez-Castillo, O. R., Meléndez-Rodríguez, M., Sánchez-Zavala, M., Cano-Escudero, I. C., Bautista-Hernández, C. I., Cruz-Borbolla, J., Morales-Ríos, M. S., & Joseph-Nathan, P. (2012). Absolute configuration assignment of 3-indolylacetate esters. Tetrahedron: Asymmetry 23, 1279-1293.
Abstract
Herein we describe a straightforward method for the determination of the absolute configuration of 3-indolyl(bromo)acetate 7, 3-indolyl(alkoxy)acetates 8a?f and 3-indolyl(amino)acetate 8g, based on 1H NMR spectral analysis. The conformational preferences for two diastereomeric esters were calculated by DFT, which matched very well with the experimental results. X-ray diffraction analysis allowed us to validate the methodology, and independent absolute configuration evidence was obtained by vibrational circular dichroism.
Synthesis of Bromoindole Alkaloids from Laurencia brongniartii
Unimolecular rearrangements of ketene-O,O-acetals and fragmentations occurring in the gas phase
The absoluteconfiguration of cuauhtemone and related compounds
One-potsynthesis of conformationallyrestrictedspirooxindoles
Total Syntheses of Five Indole Alkaloids from the Marine Bryozoan Flustra foliacea
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2