Ellagitannins from Geranium potentillaefolium and G. bellum

The aerial parts of Geranium potentillaefoium afforded geraniin (1), corilagin (2), gallic acid (4), methyl gallate (6), methylbrevifolincarboxylate (7), quercetin, quercetin 3-O-?-D-glucopyranoside, quercetin 3-O-?-D-[6?-O-galloyl)glucopyranoside,kaempferol, ?-sitosterol 3-O-?-D-glucopyranoside and ?-sitosterol, while the aerial parts of G. bellum gave the samecompounds in addition to kaempferol 3-O-?-D-glucopyranoside, isolated instead of kaempferol. The substances were identifiedby 1D and 2D NMR spectroscopy in comparison with published data. The water decoction preparations from air-dried plantmaterials (2.5 g) contain ca. 4.6 % of the ellagitannin 1, envisaging that when such decoction is ingested (250 mL), atherapeutic dose of ca. 36 mg of the antitumor ellagic acid (3) may be incorporated into the organism.Keywords: Geranium potentillaefolium, Geranium bellum, chemical composition, ellagitannins, antitumor compounds