Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2
Suárez Castillo, Oscar Rodolfo
2007
Cleavage of alkoxycarbonyl protecting groups from carbamates by t-BuNH2. Oscar R. Suárez-Castillo, Luis Alberto Montiel-Ortega, Myriam Meléndez-Rodríguez, Maricruz Sánchez-Zavala. DOI: http://dx.doi.org/10.1016/j.tetlet.2006.11.024
Abstract
An efficient, simple protocol for the selective cleavage of a variety of N-alkoxycarbonyl protecting groups by t-BuNH2/MeOH is described. The scope of the procedure was explored for a series of indole, aniline and pyrrolidine carbamate derivatives containing other potentially reactive functional groups affording a clean cleavage of the carbamate group.
Artículos relacionados
One-potsynthesis of conformationallyrestrictedspirooxindoles
Configuration, stereodynamics and crystal structure of 3-substituted-2-oxofuro[2,3-b]indoles
Stereochemical assignment of naturally occurring 2,3-epoxy-2-methylbutanoate esters
The absoluteconfiguration of cuauhtemone and related compounds
Transesterifications mediated by t-BuNH2
First Total Synthesis of ()-Flustraminol B
Synthesis of 6-bromo-2-arylindoles using 2-iodobenzoic acid as precursor