2002
Alejandro Alvarez Hernandez and William R. Roush. Recent advances in the synthesis, design and selection of cysteine protease inhibitors. Current Opinion in Chemical Biology, 2002, 6, 459-465. ISSN: 1367-5931. Elsevier. Londres.
Abstract
Inhibition of cysteine proteases is emerging as an important strategy for the treatment of a variety of human diseases. Intense efforts involving structure-based inhibitor design have been directed toward several cysteine proteases, including cathepsin K, calpain, human rhinovirus 3C protease and several parasitic cysteine protease targets. Other successful recent efforts have involved combinatorial synthesis and screening for identification of new inhibitor templates.
Facile synthesis of 1,3,6-oxadiazepines from 2,2?-(1,2-ethanediyldiimino)bisphenols
Furocoumarins of three species of the genus Dorstenia
Diastereoselective alkylation of chiral glycinate derivatives containing the ?-phenylethyl group.
Phenylmethyl 2,3,4-tri-O-acetyl--D-fucopyranoside
Study of the reactivity of squarylferrocenes. Addition of amines and aminoesters
Stereoselective addition of allylmagnesium chloride to the CN bond of [4.3.0] boron heterobicycles